Repositioning Candidate Details
| Candidate ID: | R0417 |
| Source ID: | DB03796 |
| Source Type: | approved |
| Compound Type: | small molecule |
| Compound Name: | Palmitic Acid |
| Synonyms: | |
| Molecular Formula: | C16H32O2 |
| SMILES: | CCCCCCCCCCCCCCCC(O)=O |
| Structure: |
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| DrugBank Description: | A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids. |
| CAS Number: | 57-10-3 |
| Molecular Weight: | 256.4241 |
| DrugBank Indication: | |
| DrugBank Pharmacology: | Palmitic acid is the first fatty acid produced during lipogenesis (fatty acid synthesis) and from which longer fatty acids can be produced. Palmitate negatively feeds back on acetyl-CoA carboxylase (ACC) which is responsible for converting acetyl-ACP to malonyl-ACP on the growing acyl chain, thus preventing further palmitate generation |
| DrugBank MoA: | |
| Targets: | Alpha-lactalbumin; Peroxisome proliferator-activated receptor alpha; Rhodopsin; Palmitoyl-protein thioesterase 1; Myelin P2 protein; Glycodelin; Hepatocyte nuclear factor 4-gamma; Lipid binding protein; Cytochrome P450 2C8; Trafficking protein particle complex subunit 3; Fatty acid-binding protein TM_1468 |
| Inclusion Criteria: |
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| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
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| Diseases ID | DO ID | Disease Name | Definition | Class |
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