In vitro & In vivo Models
In vitro & in vivo models of CKD are manually extracted from research articles.
157 records.
| Model ID | Category | Class | Type | Model | Description | Source | Reference (PMIDs) |
|---|---|---|---|---|---|---|---|
| M001 | In vitro | Cell line | Cell line | 293F | Inhibition of recombinant human preprorenin expressed in human 293F cells using angiotensinogen as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by ELISA | Homo sapiens | 27774132 |
| M002 | In vitro | Cell line | Cell line | 293H-DA | Agonist activity at PPARgamma LBD in human 293H DA cells after 16 hrs by TR-FRET activation reporter assay | Homo sapiens | 22582973 |
| M003 | In vitro | Cell line | Cell line | 293T | Effect on human PPARgamma transactivation in 293T cells | Homo sapiens | 16546385 |
| M004 | In vitro | Cell line | Cell line | 3T3 | 3T3 (Fibroblast cells) | Homo sapiens | 31804076 |
| M005 | In vitro | Cell line | Cell line | 3T3-L1 | 3T3-L1 (Fibroblast cells) | Mus musculus | 17292606 |
| M006 | In vitro | Cell line | Tumor-derived cell line | A-431 | A-431 (Epidermoid carcinoma cells) | Homo sapiens | 19303309 |
| M007 | In vitro | Cell line | Cell line | A14 [Human melanoma] | Inhibition of INSR (unknown origin) autophosphorylation expressed in human A14 cells by ELISA-based assay | Homo sapiens | 26629594 |
| M008 | In vitro | Cell line | Tumor-derived cell line | A549 | A549 (Lung carcinoma cells) | Homo sapiens | 33423463 |
| M009 | In vitro | Cell line | Cell line | A673 | A673 | Homo sapiens | |
| M010 | In vitro | Cell line | Cell line | AN3-CA | AN3-CA | Homo sapiens | |
| M011 | In vitro | Cell line | Cell line | Ac2F | Agonist activity at full length human PPARgamma transfected in rat Ac2F cells cotransfected with PPRE-TK-luc assessed as induction of transactivation activity at 10 ug/ml by luciferase reporter gene assay relative to control | Homo sapiens | 23189988 |
| M012 | In vitro | Cell line | Cell line | Adipocyte | Adipocytes | Homo sapiens | 33142057 |
| M013 | In vitro | Cell line | Cell line | Adipose tissue derived mesenchymal stem cell | Agonist activity at human PPAR-gamma in human Adipose tissue derived mesenchymal stem cells assessed as increase in adipogenesis at 2 uM incubated for 13 days with media exchanged every 48-72 hrs by Oil-red O staining based analysis | Homo sapiens | 36533416 |
| M014 | In vitro | Cell line | Cell line | BHK | Compound was evaluated for its binding affinity towards cloned human Glucagon receptor in BHK cells | Homo sapiens | 9857085 |
| M015 | In vitro | Cell line | Cell line | BHK-21 | BHK-21 (Kidney cells) | Mesocricetus auratus | 15387654 |
| M016 | In vitro | Cell line | Cell line | BL21 | Inhibitory concentration against human PTP1B expressed in Escherichia coli BL21 cells | Homo sapiens | 16039123 |
| M017 | In vitro | Cell line | Cell line | BL21-DE3 | Inhibitory potency against human Protein-tyrosine phosphatase 1B expressed in Escherichia coli BL21 (DE3) cells | Homo sapiens | 12852970 |
| M018 | In vitro | Cell line | Cell line | BMMSC | Partial agonist activity at PPARgamma in human BMMSC cells assessed as inhibition of pioglitazone-induced adiponectin synthesis measured after 5 days by ELISA | Homo sapiens | 31865018 |
| M019 | In vitro | Cell line | Cell line | BaF3 | BaF3 (IL-3-dependent pro-B-cells) | Mus musculus | 18793846 |
| M020 | In vitro | Tissue model | Blood | Blood | Reduction of blood glucose level in alloxan induced diabetic mice at 200 mg/kg | Mus musculus | 16359864 |