Repositioning Candidates
Repositioning candidates for CKD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and CKD-associated disease in CKDdb are presented with knowledge graphs.
stats1
stats2
stats3
546 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0001 | DB00007 | approved; investigational | small molecule | Leuprolide | Details | |
| R0002 | DB00014 | approved | small molecule | Goserelin | Details | |
| R0003 | DB00050 | approved; investigational | small molecule | Cetrorelix | Details | |
| R0004 | DB00114 | approved; investigational; nutraceutical | small molecule | Pyridoxal phosphate | Details | |
| R0005 | DB00117 | investigational; nutraceutical | small molecule | Histidine | Details | |
| R0006 | DB00120 | approved; investigational; nutraceutical | small molecule | Phenylalanine | Details | |
| R0007 | DB00121 | approved; investigational; nutraceutical | small molecule | Biotin | Details | |
| R0008 | DB00122 | approved; nutraceutical | small molecule | Choline | Details | |
| R0009 | DB00123 | approved; nutraceutical | small molecule | L-Lysine | Details | |
| R0010 | DB00125 | investigational; nutraceutical | small molecule | Arginine | Details | |
| R0011 | DB00126 | approved; nutraceutical | small molecule | Ascorbic acid | Details | |
| R0012 | DB00128 | approved; nutraceutical | small molecule | Aspartic acid | Details | |
| R0013 | DB00129 | approved; nutraceutical | small molecule | Ornithine | Details | |
| R0014 | DB00130 | approved; investigational; nutraceutical | small molecule | L-Glutamine | Details | |
| R0015 | DB00133 | investigational; nutraceutical | small molecule | Serine | Details | |
| R0016 | DB00134 | approved; nutraceutical | small molecule | Methionine | Details | |
| R0017 | DB00135 | approved; investigational; nutraceutical | small molecule | Tyrosine | Details | |
| R0018 | DB00136 | approved; nutraceutical | small molecule | Calcitriol | Details | |
| R0019 | DB00137 | approved; investigational; nutraceutical | small molecule | Lutein | Details | |
| R0020 | DB00140 | approved; investigational; nutraceutical; vet_approved | small molecule | Riboflavin | Details | |
| R0021 | DB00142 | approved; nutraceutical | small molecule | Glutamic acid | Details | |
| R0022 | DB00144 | approved; investigational; nutraceutical | small molecule | Phosphatidyl serine | Details | |
| R0023 | DB00145 | approved; nutraceutical; vet_approved | small molecule | Glycine | Details | |
| R0024 | DB00146 | approved; nutraceutical | small molecule | Calcifediol | Details | |
| R0025 | DB00147 | experimental; nutraceutical | small molecule | Pyridoxal | Details | |
| R0026 | DB00148 | approved; investigational; nutraceutical | small molecule | Creatine | Details | |
| R0027 | DB00149 | investigational; nutraceutical | small molecule | Leucine | Details | |
| R0028 | DB00150 | approved; nutraceutical; withdrawn | small molecule | Tryptophan | Details | |
| R0029 | DB00151 | approved; nutraceutical | small molecule | Cysteine | Details | |
| R0030 | DB00152 | approved; investigational; nutraceutical; vet_approved | small molecule | Thiamine | Details | |
| R0031 | DB00153 | approved; nutraceutical | small molecule | Ergocalciferol | Details | |
| R0032 | DB00156 | approved; nutraceutical | small molecule | Threonine | Details | |
| R0033 | DB00160 | nutraceutical | small molecule | Alanine | Details | |
| R0034 | DB00161 | approved; nutraceutical | small molecule | Valine | Details | |
| R0035 | DB00162 | approved; nutraceutical; vet_approved | small molecule | Vitamin A | Details | |
| R0036 | DB00163 | approved; nutraceutical; vet_approved | small molecule | Vitamin E | Details | |
| R0037 | DB00165 | approved; investigational; nutraceutical; vet_approved | small molecule | Pyridoxine | Details | |
| R0038 | DB00167 | investigational; nutraceutical | small molecule | Isoleucine | Details | |
| R0039 | DB00169 | approved; nutraceutical | small molecule | Cholecalciferol | Details | |
| R0040 | DB00170 | approved; nutraceutical | small molecule | Menadione | Details | |
| R0041 | DB00172 | nutraceutical | small molecule | Proline | Details | |
| R0042 | DB00175 | approved | small molecule | Pravastatin | Details | |
| R0043 | DB00177 | approved; investigational | small molecule | Valsartan | Details | |
| R0044 | DB00178 | approved | small molecule | Ramipril | Details | |
| R0045 | DB00187 | approved | small molecule | Esmolol | Details | |
| R0046 | DB00188 | approved; investigational | small molecule | Bortezomib | Details | |
| R0047 | DB00191 | approved; illicit | small molecule | Phentermine | Details | |
| R0048 | DB00193 | approved; investigational | small molecule | Tramadol | Details | |
| R0049 | DB00196 | approved; investigational | small molecule | Fluconazole | Details | |
| R0050 | DB00197 | approved; investigational; withdrawn | small molecule | Troglitazone | Details | |
| R0051 | DB00198 | approved | small molecule | Oseltamivir | Details | |
| R0052 | DB00199 | approved; investigational; vet_approved | small molecule | Erythromycin | Details | |
| R0053 | DB00201 | approved | small molecule | Caffeine | Details | |
| R0054 | DB00206 | approved; investigational | small molecule | Reserpine | Details | |
| R0055 | DB00207 | approved | small molecule | Azithromycin | Details | |
| R0056 | DB00213 | approved | small molecule | Pantoprazole | Details | |
| R0057 | DB00214 | approved | small molecule | Torasemide | Details | |
| R0058 | DB00215 | approved | small molecule | Citalopram | Details | |
| R0059 | DB00218 | approved; investigational | small molecule | Moxifloxacin | Details | |
| R0060 | DB00224 | approved | small molecule | Indinavir | Details | |
| R0061 | DB00227 | approved; investigational | small molecule | Lovastatin | Details | |
| R0062 | DB00230 | approved; investigational | small molecule | Pregabalin | Details | |
| R0063 | DB00238 | approved | small molecule | Nevirapine | Details | |
| R0064 | DB00243 | approved; investigational | small molecule | Ranolazine | Details | |
| R0065 | DB00246 | approved | small molecule | Ziprasidone | Details | |
| R0066 | DB00254 | approved; investigational; vet_approved | small molecule | Doxycycline | Details | |
| R0067 | DB00257 | approved; vet_approved | small molecule | Clotrimazole | Details | |
| R0068 | DB00264 | approved; investigational | small molecule | Metoprolol | Details | |
| R0069 | DB00268 | approved; investigational | small molecule | Ropinirole | Details | |
| R0070 | DB00269 | investigational; withdrawn | small molecule | Chlorotrianisene | Details | |
| R0071 | DB00273 | approved | small molecule | Topiramate | Details | |
| R0072 | DB00275 | approved; investigational | small molecule | Olmesartan | Details | |
| R0073 | DB00277 | approved | small molecule | Theophylline | Details | |
| R0074 | DB00281 | approved; vet_approved | small molecule | Lidocaine | Details | |
| R0075 | DB00282 | approved | small molecule | Pamidronic acid | Details | |
| R0076 | DB00291 | approved | small molecule | Chlorambucil | Details | |
| R0077 | DB00295 | approved; investigational | small molecule | Morphine | Details | |
| R0078 | DB00297 | approved; investigational | small molecule | Bupivacaine | Details | |
| R0079 | DB00302 | approved | small molecule | Tranexamic acid | Details | |
| R0080 | DB00303 | approved; investigational | small molecule | Ertapenem | Details | |
| R0081 | DB00305 | approved | small molecule | Mitomycin | Details | |
| R0082 | DB00310 | approved | small molecule | Chlorthalidone | Details | |
| R0083 | DB00313 | approved; investigational | small molecule | Valproic acid | Details | |
| R0084 | DB00316 | approved | small molecule | Acetaminophen | Details | |
| R0085 | DB00319 | approved | small molecule | Piperacillin | Details | |
| R0086 | DB00321 | approved | small molecule | Amitriptyline | Details | |
| R0087 | DB00325 | approved; investigational | small molecule | Nitroprusside | Details | |
| R0088 | DB00328 | approved; investigational | small molecule | Indomethacin | Details | |
| R0089 | DB00331 | approved | small molecule | Metformin | Details | |
| R0090 | DB00333 | approved | small molecule | Methadone | Details | |
| R0091 | DB00334 | approved; investigational | small molecule | Olanzapine | Details | |
| R0092 | DB00335 | approved | small molecule | Atenolol | Details | |
| R0093 | DB00341 | approved | small molecule | Cetirizine | Details | |
| R0094 | DB00343 | approved; investigational | small molecule | Diltiazem | Details | |
| R0095 | DB00350 | approved; investigational | small molecule | Minoxidil | Details | |
| R0096 | DB00356 | approved | small molecule | Chlorzoxazone | Details | |
| R0097 | DB00363 | approved | small molecule | Clozapine | Details | |
| R0098 | DB00367 | approved; investigational | small molecule | Levonorgestrel | Details | |
| R0099 | DB00368 | approved | small molecule | Norepinephrine | Details | |
| R0100 | DB00369 | approved | small molecule | Cidofovir | Details |