Repositioning Candidate Details
| Candidate ID: | R0409 |
| Source ID: | DB02701 |
| Source Type: | approved; investigational |
| Compound Type: | small molecule |
| Compound Name: | Nicotinamide |
| Synonyms: | |
| Molecular Formula: | C6H6N2O |
| SMILES: | NC(=O)C1=CC=CN=C1 |
| Structure: |
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| DrugBank Description: | An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. |
| CAS Number: | 98-92-0 |
| Molecular Weight: | 122.1246 |
| DrugBank Indication: | |
| DrugBank Pharmacology: | |
| DrugBank MoA: | |
| Targets: | ADP-ribosyl cyclase 2; Exotoxin A; NAD-dependent protein deacylase sirtuin-5, mitochondrial; L-lactate dehydrogenase A chain; Poly [ADP-ribose] polymerase 1 |
| Inclusion Criteria: |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
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| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
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| Diseases ID | DO ID | Disease Name | Definition | Class |
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