Repositioning Candidate Details
| Candidate ID: | R0545 |
| Source ID: | DB14973 |
| Source Type: | investigational |
| Compound Type: | small molecule |
| Compound Name: | Abrocitinib |
| Synonyms: | |
| Molecular Formula: | C14H21N5O2S |
| SMILES: | CCCS(=O)(=O)N[C@H]1C[C@H](C1)N(C)C1=C2C=CNC2=NC=N1 |
| Structure: |
|
| DrugBank Description: | Abrocitinib is under investigation in clinical trial NCT03796676 (JAK1 Inhibitor With Medicated Topical Therapy in Adolescents With Atopic Dermatitis). |
| CAS Number: | 1622902-68-4 |
| Molecular Weight: | 323.42 |
| DrugBank Indication: | |
| DrugBank Pharmacology: | |
| DrugBank MoA: | |
| Targets: | Tyrosine-protein kinase JAK1; Tyrosine-protein kinase JAK2; Tyrosine-protein kinase JAK3; Non-receptor tyrosine-protein kinase TYK2 |
| Inclusion Criteria: |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class |
|---|