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CMap Candidate Details

Structure:
CMap ID: C01006
Pert ID: BRD-K60240222
Compound Name: carglumic-acid
Targets: CPS1
MoA: carbamoyl phosphate synthase activator
SMILES: NC(=O)N[C@@H](CCC(O)=O)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123815 BRD-K60240222 A375 0.37 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.52
123856 BRD-K60240222 A549 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123877 BRD-K60240222 HA1E 0.04 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
123925 BRD-K60240222 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123953 BRD-K60240222 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123974 BRD-K60240222 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124027 BRD-K60240222 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124078 BRD-K60240222 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124106 BRD-K60240222 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
124143 BRD-K60240222 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 -0.21 -0.69 0.02
124208 BRD-K60240222 THP1 1.11 uM 24 h 0.24 1.02 0.12 0.0 0.0 0.0
124261 BRD-K60240222 YAPC 0.04 uM 24 h -0.19 -0.79 0.0 -0.21 -0.69 0.02
132314 BRD-K60240222 PC3 0.08 uM 24 h -0.26 -1.08 0.28 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).