CMap Candidate Details
Structure:
| CMap ID: | C01009 |
| Pert ID: | BRD-K57764956 |
| Compound Name: | cariprazine |
| Targets: | DRD2|DRD3 |
| MoA: | dopamine receptor antagonist |
| SMILES: | CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123520 | BRD-K57764956 | A375 | 0.125 uM | 24 h | -0.27 | -1.12 | 0.39 | 0.32 | 1.12 | 0.75 |
| 123542 | BRD-K57764956 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123583 | BRD-K57764956 | HEK293 | 0.04 uM | 24 h | 0.26 | 1.1 | 0.24 | 0.0 | 0.0 | 0.0 |
| 123657 | BRD-K57764956 | HT29 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.16 | 1.11 |
| 123699 | BRD-K57764956 | MCF10A | 10 uM | 24 h | 0.24 | 0.99 | 0.1 | 0.0 | 0.0 | 0.0 |
| 123726 | BRD-K57764956 | MCF??7.00 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.74 | 0.06 |
| 123769 | BRD-K57764956 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132043 | BRD-K57764956 | HELA | 0.03 uM | 24 h | 0.28 | 1.16 | 0.34 | 0.32 | 1.12 | 0.74 |
| 132121 | BRD-K57764956 | PC3 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |