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CMap Candidate Details

Structure:
CMap ID: C01010
Pert ID: BRD-A99939097
Compound Name: carisoprodol
Targets: CYP2C19
MoA: acetylcholine receptor antagonist
SMILES: CCCC(C)(COC(N)=O)COC(=O)NC(C)C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127756 BRD-A99939097 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127799 BRD-A99939097 A549 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127884 BRD-A99939097 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127906 BRD-A99939097 HT29 0.37 uM 24 h 0.18 0.75 0.0 0.28 0.99 0.42
127958 BRD-A99939097 HUVEC 0.125 uM 24 h -0.25 -1.03 0.2 0.29 1.03 0.5
128008 BRD-A99939097 MCF10A 10 uM 24 h -0.23 -0.97 0.11 0.0 0.0 0.0
128091 BRD-A99939097 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135532 BRD-A99939097 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135585 BRD-A99939097 HELA 0.08 uM 24 h -0.2 -0.84 0.01 0.31 1.09 0.67
135676 BRD-A99939097 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135704 BRD-A99939097 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135728 BRD-A99939097 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.39 1.38 2.15
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).