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CMap Candidate Details

Structure:
CMap ID: C01021
Pert ID: BRD-A42167015
Compound Name: carteolol
Targets: ADRB1|ADRB2
MoA: adrenergic receptor antagonist
SMILES: CC(C)(C)NCC(O)COc1cccc2NC(=O)CCc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4173 BRD-A42167015 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4305 BRD-A42167015 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4620 BRD-A42167015 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4996 BRD-A42167015 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.96 0.44
37079 BRD-A42167015 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37238 BRD-A42167015 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37501 BRD-A42167015 ASC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
37823 BRD-A42167015 HEPG2 10 uM 6 h 0.31 1.28 0.62 -0.32 -1.09 0.82
38017 BRD-A42167015 HT29 10 uM 6 h 0.0 0.0 0.0 0.31 1.08 0.66
38351 BRD-A42167015 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38640 BRD-A42167015 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38860 BRD-A42167015 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51673 BRD-A42167015 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).