CMap Candidate Details
Structure:
| CMap ID: | C01034 |
| Pert ID: | BRD-K59929863 |
| Compound Name: | CB-10-277 |
| Targets: | |
| MoA: | DNA synthesis inhibitor |
| SMILES: | CN(C)\N=N\c1ccc(cc1)C(O)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123814 | BRD-K59929863 | A375 | 10 uM | 24 h | 0.29 | 1.19 | 0.42 | 0.0 | 0.0 | 0.0 |
| 123854 | BRD-K59929863 | A549 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -0.99 | 0.51 |
| 123923 | BRD-K59929863 | HEK293 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.05 | 0.57 |
| 123972 | BRD-K59929863 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124025 | BRD-K59929863 | JURKAT | 0.125 uM | 24 h | -0.29 | -1.23 | 0.63 | -0.34 | -1.14 | 1.03 |
| 124076 | BRD-K59929863 | MCF10A | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124141 | BRD-K59929863 | MDAMB231 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.87 | 0.23 |
| 124206 | BRD-K59929863 | THP1 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.12 | 0.93 |
| 124259 | BRD-K59929863 | YAPC | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.87 | 0.23 |
| 132179 | BRD-K59929863 | HA1E | 0.08 uM | 24 h | -0.22 | -0.91 | 0.05 | -0.26 | -0.88 | 0.25 |
| 132210 | BRD-K59929863 | HELA | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132266 | BRD-K59929863 | MCF??7.00 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132312 | BRD-K59929863 | PC3 | 0.74 uM | 24 h | 0.28 | 1.18 | 0.4 | 0.0 | 0.0 | 0.0 |