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CMap Candidate Details

Structure:
CMap ID: C01043
Pert ID: BRD-K48213016
Compound Name: CC-930
Targets:
MoA: JNK inhibitor
SMILES: O[C@H]1CC[C@@H](CC1)Nc1ncc2nc(Nc3c(F)cc(F)cc3F)n([C@H]3CCOC3)c2n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125241 BRD-K48213016 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125260 BRD-K48213016 A549 3.33 uM 24 h -0.28 -1.18 0.51 0.26 0.93 0.27
125282 BRD-K48213016 HA1E 3.33 uM 24 h 0.25 1.06 0.18 -0.29 -0.96 0.44
125319 BRD-K48213016 HEK293 0.125 uM 24 h -0.29 -1.22 0.61 -0.24 -0.8 0.12
125354 BRD-K48213016 HELA 0.125 uM 24 h 0.33 1.38 0.97 0.0 0.0 0.0
125375 BRD-K48213016 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125401 BRD-K48213016 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125417 BRD-K48213016 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125450 BRD-K48213016 MCF??7.00 0.125 uM 24 h -0.29 -1.2 0.55 -0.28 -0.93 0.34
125475 BRD-K48213016 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125497 BRD-K48213016 PC3 0.125 uM 24 h -0.29 -1.22 0.62 0.0 0.0 0.0
125523 BRD-K48213016 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133635 BRD-K48213016 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).