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CMap Candidate Details

Structure:
CMap ID: C01050
Pert ID: BRD-K90999434
Compound Name: CCT-031374
Targets: CTNNB1
MoA: WNT signaling inhibitor
SMILES: O=C(CN1C2=NCCN2c2ccccc12)c1ccc(cc1)-c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9007 BRD-K90999434 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9125 BRD-K90999434 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9542 BRD-K90999434 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9954 BRD-K90999434 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10326 BRD-K90999434 HCC515 10 uM 6 h 0.0 0.0 0.0 0.26 0.94 0.28
10875 BRD-K90999434 HEPG2 10 uM 6 h 0.18 0.75 0.0 0.25 0.87 0.17
11038 BRD-K90999434 HT29 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.87
11208 BRD-K90999434 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12165 BRD-K90999434 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12528 BRD-K90999434 PC3 10 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
12898 BRD-K90999434 SW480 10 uM 6 h 0.0 0.0 0.0 0.23 0.8 0.08
13393 BRD-K90999434 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13705 BRD-K90999434 VCAP 10 uM 6 h 0.22 0.92 0.04 0.34 1.2 1.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).