CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01085
Pert ID:	BRD-K02292852
Compound Name:	cefoperazone
Targets:
MoA:	bacterial cell wall synthesis inhibitor
SMILES:	CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(CSc4nnnn4C)=C(N3C2=O)C(O)=O)c2ccc(O)cc2)C(=O)C1=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
91429	BRD-K02292852	HUH7	4 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
117781	BRD-K02292852	HA1E	3.33 uM	24 h	0.2	0.84	0.0	0.0	0.0	0.0
117832	BRD-K02292852	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
117882	BRD-K02292852	HEPG2	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122900	BRD-K02292852	HEK293	0.37 uM	24 h	-0.24	-0.98	0.13	0.22	0.79	0.07
122976	BRD-K02292852	HT29	0.04 uM	24 h	0.27	1.11	0.26	-0.31	-1.04	0.66
123025	BRD-K02292852	JURKAT	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123115	BRD-K02292852	MDAMB231	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123148	BRD-K02292852	PC3	0.37 uM	24 h	0.0	0.0	0.0	-0.3	-1.0	0.55
123186	BRD-K02292852	THP1	0.125 uM	24 h	0.17	0.69	0.0	0.0	0.0	0.0
131212	BRD-K02292852	A375	0.25 uM	24 h	-0.26	-1.08	0.3	0.0	0.0	0.0
131248	BRD-K02292852	A549	0.01 uM	24 h	0.0	0.0	0.0	-0.28	-0.93	0.35
131308	BRD-K02292852	HELA	2.22 uM	24 h	-0.3	-1.24	0.67	0.21	0.76	0.05
131362	BRD-K02292852	HUVEC	0.03 uM	24 h	0.26	1.09	0.23	0.0	0.0	0.0
131402	BRD-K02292852	MCF10A	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131440	BRD-K02292852	MCF??7.00	0.25 uM	24 h	0.0	0.0	0.0	-0.36	-1.23	1.25
131499	BRD-K02292852	YAPC	0.01 uM	24 h	0.18	0.74	0.0	-0.22	-0.73	0.05

Summary