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CMap Candidate Details

Structure:
CMap ID: C01090
Pert ID: BRD-K02275692
Compound Name: cefotiam
Targets:
MoA: bacterial cell wall synthesis inhibitor
SMILES: CN(C)CCn1nnnc1SCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc1csc(N)n1)C2=O)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1721 BRD-K02275692 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1864 BRD-K02275692 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2361 BRD-K02275692 PC3 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.0 0.52
2508 BRD-K02275692 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41700 BRD-K02275692 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42042 BRD-K02275692 A549 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.19 1.16
42259 BRD-K02275692 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42595 BRD-K02275692 HEPG2 10 uM 6 h -0.25 -1.04 0.22 -0.33 -1.1 0.86
42900 BRD-K02275692 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43280 BRD-K02275692 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.9 0.28
43455 BRD-K02275692 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
43762 BRD-K02275692 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).