CMap Candidate Details
Structure:
| CMap ID: | C01112 |
| Pert ID: | BRD-K20722021 |
| Compound Name: | CEP-32496 |
| Targets: | BRAF|RAF1 |
| MoA: | RAF inhibitor |
| SMILES: | COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C(F)(F)F)c3)c2cc1OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121365 | BRD-K20722021 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.79 | 0.08 |
| 121385 | BRD-K20722021 | HA1E | 10 uM | 24 h | -0.26 | -1.07 | 0.28 | 0.0 | 0.0 | 0.0 |
| 121408 | BRD-K20722021 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121461 | BRD-K20722021 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121479 | BRD-K20722021 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121512 | BRD-K20722021 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129492 | BRD-K20722021 | HT29 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |