CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01142
Pert ID:	BRD-A40084411
Compound Name:	CGP-12177
Targets:	ADRB1\|ADRB2\|ADRB3
MoA:	adrenergic receptor agonist
SMILES:	CC(C)(C)NCC(O)COc1cccc2[nH]c(O)nc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
123234	BRD-A40084411	A375	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123311	BRD-A40084411	HELA	0.125 uM	24 h	0.0	0.0	0.0	-0.26	-0.87	0.24
123396	BRD-A40084411	MDAMB231	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123420	BRD-A40084411	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131549	BRD-A40084411	A549	0.08 uM	24 h	0.22	0.9	0.03	0.0	0.0	0.0
131584	BRD-A40084411	HA1E	2.22 uM	24 h	0.0	0.0	0.0	-0.23	-0.78	0.1
131625	BRD-A40084411	HEK293	2.22 uM	24 h	0.22	0.9	0.02	0.0	0.0	0.0
131685	BRD-A40084411	HT29	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131722	BRD-A40084411	HUVEC	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131775	BRD-A40084411	JURKAT	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131822	BRD-A40084411	MCF10A	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131854	BRD-A40084411	MCF??7.00	0.01 uM	24 h	0.19	0.79	0.0	-0.34	-1.16	1.11
131932	BRD-A40084411	THP1	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131951	BRD-A40084411	YAPC	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary