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CMap Candidate Details

Structure:
CMap ID: C00115
Pert ID: BRD-K01577834
Compound Name: adenosine
Targets: ADORA1|ADORA2A|ADORA2B|ADORA3|PI4K2A|PI4K2B|TRPM4
MoA: adenosine receptor agonist
SMILES: Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122832 BRD-K01577834 A375 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122891 BRD-K01577834 HEK293 10 uM 24 h -0.31 -1.28 0.74 0.0 0.0 0.0
122938 BRD-K01577834 HELA 10 uM 24 h 0.0 0.0 0.0 0.38 1.35 1.72
122970 BRD-K01577834 HT29 0.04 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
123016 BRD-K01577834 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123062 BRD-K01577834 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.42
123105 BRD-K01577834 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.26 0.9 0.23
123177 BRD-K01577834 THP1 0.125 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.44
131241 BRD-K01577834 A549 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131276 BRD-K01577834 HA1E 0.01 uM 24 h 0.25 1.06 0.19 0.0 0.0 0.0
131353 BRD-K01577834 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131432 BRD-K01577834 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131460 BRD-K01577834 PC3 2.22 uM 24 h -0.21 -0.89 0.04 0.24 0.86 0.16
131492 BRD-K01577834 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.9
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).