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CMap Candidate Details

Structure:
CMap ID: C01150
Pert ID: BRD-A89672324
Compound Name: CGP-55845
Targets: GABBR1|GABBR2|KCTD12|KCTD16|KCTD8
MoA: GABA receptor antagonist
SMILES: C[C@H](NC[C@H](O)CP(O)(=O)Cc1ccccc1)c1ccc(Cl)c(Cl)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1712 BRD-A89672324 HA1E 10 uM 6 h -0.21 -0.87 0.02 0.21 0.73 0.03
1853 BRD-A89672324 HCC515 10 uM 24 h -0.21 -0.86 0.02 -0.26 -0.89 0.26
2746 BRD-A89672324 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39289 BRD-A89672324 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39607 BRD-A89672324 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39927 BRD-A89672324 HEPG2 10 uM 6 h 0.29 1.22 0.48 0.0 0.0 0.0
40211 BRD-A89672324 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40442 BRD-A89672324 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40730 BRD-A89672324 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41032 BRD-A89672324 NPC 10 uM 24 h 0.0 0.0 0.0 0.2 0.72 0.02
41355 BRD-A89672324 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97142 BRD-A89672324 A375 3.33 uM 24 h 0.22 0.91 0.04 0.0 0.0 0.0
97208 BRD-A89672324 PC3 1.11 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).