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CMap Candidate Details

Structure:
CMap ID: C01196
Pert ID: BRD-A91699651
Compound Name: chloroquine
Targets: GSTA2|MRGPRX1|TLR9|TNF
MoA: antimalarial agent
SMILES: CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5288 BRD-A91699651 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.16
9320 BRD-A91699651 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9623 BRD-A91699651 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10141 BRD-A91699651 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10698 BRD-A91699651 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11375 BRD-A91699651 NCIH2073 10 uM 6 h -0.22 -0.9 0.04 0.0 0.0 0.0
11679 BRD-A91699651 NCIH508 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.68
11945 BRD-A91699651 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12694 BRD-A91699651 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12969 BRD-A91699651 THP1 10 uM 6 h 0.0 0.0 0.0 0.22 0.77 0.05
13173 BRD-A91699651 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13433 BRD-A91699651 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44796 BRD-A91699651 ASC 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
45916 BRD-A91699651 NPC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.77
46233 BRD-A91699651 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46546 BRD-A91699651 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90569 BRD-A91699651 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91461 BRD-A91699651 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
98982 BRD-A91699651 NEU 10 uM 6 h -0.27 -1.13 0.41 0.0 0.0 0.0
100391 BRD-A91699651 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
127748 BRD-A91699651 A375 0.125 uM 24 h -0.33 -1.39 1.09 -0.37 -1.25 1.35
127873 BRD-A91699651 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127947 BRD-A91699651 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128000 BRD-A91699651 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
135574 BRD-A91699651 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135617 BRD-A91699651 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135665 BRD-A91699651 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
135699 BRD-A91699651 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135723 BRD-A91699651 PC3 0.01 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
135747 BRD-A91699651 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).