CMap Candidate Details
Structure:
| CMap ID: | C00122 |
| Pert ID: | BRD-K34870043 |
| Compound Name: | adoprazine |
| Targets: | DRD2|HTR1A |
| MoA: | dopamine receptor antagonist; serotonin receptor agonist |
| SMILES: | Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2cccc3OCCOc23)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120531 | BRD-K34870043 | A375 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120570 | BRD-K34870043 | A549 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.29 | 1.55 |
| 120637 | BRD-K34870043 | HELA | 10 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120675 | BRD-K34870043 | HT29 | 0.04 uM | 24 h | 0.2 | 0.82 | 0.0 | 0.23 | 0.8 | 0.08 |
| 120728 | BRD-K34870043 | JURKAT | 10 uM | 24 h | -0.26 | -1.07 | 0.28 | -0.34 | -1.13 | 0.98 |
| 120836 | BRD-K34870043 | YAPC | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129009 | BRD-K34870043 | HA1E | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129063 | BRD-K34870043 | MCF??7.00 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.02 | 0.62 |
| 129084 | BRD-K34870043 | PC3 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |