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CMap Candidate Details

Structure:
CMap ID: C01283
Pert ID: BRD-K54142781
Compound Name: cirazoline
Targets: ADRA1A
MoA: adrenergic receptor agonist
SMILES: C(Oc1ccccc1C1CC1)C1=NCCN1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3039 BRD-K54142781 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3232 BRD-K54142781 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3631 BRD-K54142781 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3831 BRD-K54142781 VCAP 10 uM 24 h 0.27 1.12 0.27 0.28 0.99 0.41
44417 BRD-K54142781 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44717 BRD-K54142781 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44988 BRD-K54142781 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45281 BRD-K54142781 HEPG2 10 uM 6 h -0.24 -1.0 0.15 -0.35 -1.18 1.14
45546 BRD-K54142781 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45705 BRD-K54142781 MCF??7.00 10 uM 24 h -0.22 -0.92 0.06 -0.23 -0.78 0.09
46104 BRD-K54142781 NPC 10 uM 24 h 0.0 0.0 0.0 -0.19 -0.65 0.01
46418 BRD-K54142781 PHH 10 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
46743 BRD-K54142781 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99652 BRD-K54142781 U2OS 25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).