CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01302
Pert ID:	BRD-K00662280
Compound Name:	CL-218872
Targets:	GABRA1\|GABRA2\|GABRA3\|GABRA5\|GABRB2\|GABRG2
MoA:	benzodiazepine receptor agonist
SMILES:	Cc1nnc2ccc(nn12)-c1cccc(c1)C(F)(F)F
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
2826	BRD-K00662280	HA1E	10 uM	24 h	0.0	0.0	0.0	-0.18	-0.61	0.0
3127	BRD-K00662280	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3459	BRD-K00662280	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3712	BRD-K00662280	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39616	BRD-K00662280	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39936	BRD-K00662280	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40741	BRD-K00662280	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41366	BRD-K00662280	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99949	BRD-K00662280	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
122882	BRD-K00662280	HEK293	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123007	BRD-K00662280	JURKAT	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123055	BRD-K00662280	MCF10A	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123072	BRD-K00662280	MCF??7.00	3.33 uM	24 h	0.0	0.0	0.0	-0.36	-1.21	1.24
123096	BRD-K00662280	MDAMB231	3.33 uM	24 h	0.25	1.03	0.13	0.0	0.0	0.0
123168	BRD-K00662280	THP1	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123213	BRD-K00662280	YAPC	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131201	BRD-K00662280	A375	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131233	BRD-K00662280	A549	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131298	BRD-K00662280	HELA	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131323	BRD-K00662280	HT29	0.25 uM	24 h	0.0	0.0	0.0	-0.32	-1.07	0.75
131344	BRD-K00662280	HUVEC	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary