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CMap Candidate Details

Structure:
CMap ID: C01310
Pert ID: BRD-A75726477
Compound Name: clenbuterol
Targets: ADRB1|ADRB2|ADRB3|NGF|TNF
MoA: adrenergic receptor agonist
SMILES: CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91057 BRD-A75726477 HUH7 12 uM 72 h -0.2 -0.84 0.01 0.19 0.67 0.01
127019 BRD-A75726477 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127100 BRD-A75726477 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127209 BRD-A75726477 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
127238 BRD-A75726477 PC3 0.125 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.84
135042 BRD-A75726477 A549 0.08 uM 24 h -0.22 -0.91 0.06 0.0 0.0 0.0
135084 BRD-A75726477 HA1E 0.03 uM 24 h 0.3 1.26 0.56 0.0 0.0 0.0
135109 BRD-A75726477 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.26
135147 BRD-A75726477 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135171 BRD-A75726477 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
135207 BRD-A75726477 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135265 BRD-A75726477 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135305 BRD-A75726477 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.54
135327 BRD-A75726477 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).