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CMap Candidate Details

Structure:
CMap ID: C00133
Pert ID: BRD-K69247067
Compound Name: afloqualone
Targets:
MoA: acetylcholine receptor antagonist
SMILES: Cc1ccccc1-n1c(CF)nc2ccc(N)cc2c1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126424 BRD-K69247067 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
126515 BRD-K69247067 MCF10A 0.37 uM 24 h -0.22 -0.91 0.05 -0.32 -1.08 0.79
126532 BRD-K69247067 MCF??7.00 3.33 uM 24 h 0.24 0.98 0.09 -0.31 -1.04 0.66
126572 BRD-K69247067 PC3 0.04 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.03
134341 BRD-K69247067 A375 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134369 BRD-K69247067 A549 2.22 uM 24 h 0.28 1.18 0.39 -0.27 -0.89 0.27
134392 BRD-K69247067 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134422 BRD-K69247067 HELA 0.74 uM 24 h -0.32 -1.32 0.83 0.34 1.19 1.01
134454 BRD-K69247067 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.35 1.25 1.29
134491 BRD-K69247067 HUVEC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134590 BRD-K69247067 MDAMB231 0.08 uM 24 h 0.35 1.46 1.12 0.0 0.0 0.0
134647 BRD-K69247067 YAPC 0.01 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).