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CMap Candidate Details

Structure:
CMap ID: C01337
Pert ID: BRD-K29950728
Compound Name: clomifene
Targets: ESR1
MoA: estrogen receptor antagonist
SMILES: CCN(CC)CCOc1ccc(cc1)C(=C(/Cl)c1ccccc1)\c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5605 BRD-K29950728 HCC515 10 uM 24 h 0.22 0.92 0.04 0.33 1.19 1.01
42348 BRD-K29950728 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42674 BRD-K29950728 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.28 0.99 0.41
43539 BRD-K29950728 NPC 10 uM 24 h -0.2 -0.82 0.0 -0.36 -1.2 1.2
43837 BRD-K29950728 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44107 BRD-K29950728 SKB 10 uM 24 h 0.0 0.0 0.0 0.24 0.87 0.17
51139 BRD-K29950728 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95335 BRD-K29950728 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95462 BRD-K29950728 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121893 BRD-K29950728 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121935 BRD-K29950728 HA1E 10 uM 24 h 0.26 1.08 0.21 0.44 1.57 2.34
121955 BRD-K29950728 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121980 BRD-K29950728 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122007 BRD-K29950728 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122045 BRD-K29950728 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122139 BRD-K29950728 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.34 1.21 1.13
122163 BRD-K29950728 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122190 BRD-K29950728 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122218 BRD-K29950728 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130346 BRD-K29950728 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130395 BRD-K29950728 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.11
130430 BRD-K29950728 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).