CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01339
Pert ID:	BRD-K38183498
Compound Name:	clonazepam
Targets:	GABRA1\|GABRA2\|GABRA3\|GABRA4\|GABRA5\|GABRA6\|GABRB1\|GABRB2\|GABRB3\|GABRD\|GABRE\|GABRG1\|GABRG2\|GABRG3\|GABRP\|GABRQ\|TSPO
MoA:	GABA benzodiazepine site receptor agonist
SMILES:	[O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3Cl)c2c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1418	BRD-K38183498	NPC	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123227	BRD-K38183498	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123273	BRD-K38183498	HA1E	10 uM	24 h	0.21	0.87	0.01	0.0	0.0	0.0
123306	BRD-K38183498	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123334	BRD-K38183498	HT29	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123361	BRD-K38183498	MCF10A	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123379	BRD-K38183498	MCF??7.00	10 uM	24 h	0.25	1.06	0.18	0.0	0.0	0.0
123415	BRD-K38183498	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123486	BRD-K38183498	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131540	BRD-K38183498	A549	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131618	BRD-K38183498	HEK293	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131711	BRD-K38183498	HUVEC	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131764	BRD-K38183498	JURKAT	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131882	BRD-K38183498	MDAMB231	2.22 uM	24 h	0.29	1.2	0.43	-0.25	-0.84	0.18
131928	BRD-K38183498	THP1	0.08 uM	24 h	0.0	0.0	0.0	-0.34	-1.13	0.98

Summary