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CMap Candidate Details

Structure:
CMap ID: C01340
Pert ID: BRD-K98530306
Compound Name: clonidine
Targets: ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C
MoA: adrenergic receptor agonist
SMILES: Clc1cccc(Cl)c1N=C1NCCN1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5705 BRD-K98530306 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9556 BRD-K98530306 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10639 BRD-K98530306 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11626 BRD-K98530306 NCIH2073 10 uM 6 h 0.21 0.87 0.01 0.0 0.0 0.0
12180 BRD-K98530306 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12418 BRD-K98530306 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13405 BRD-K98530306 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13713 BRD-K98530306 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45060 BRD-K98530306 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45343 BRD-K98530306 HEPG2 10 uM 6 h 0.22 0.93 0.05 -0.28 -0.96 0.42
46169 BRD-K98530306 NPC 10 uM 24 h -0.25 -1.05 0.24 0.0 0.0 0.0
46484 BRD-K98530306 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46814 BRD-K98530306 SKB 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.11
91015 BRD-K98530306 HUH7 15 uM 72 h 0.0 0.0 0.0 -0.33 -1.1 0.86
98959 BRD-K98530306 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127338 BRD-K98530306 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127412 BRD-K98530306 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127499 BRD-K98530306 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127593 BRD-K98530306 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
127636 BRD-K98530306 THP1 0.04 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.03
127669 BRD-K98530306 YAPC 0.04 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
135340 BRD-K98530306 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135360 BRD-K98530306 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.38
135389 BRD-K98530306 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135429 BRD-K98530306 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
135463 BRD-K98530306 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.12
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).