CMap Candidate Details
Structure:
| CMap ID: | C01352 |
| Pert ID: | BRD-A19952358 |
| Compound Name: | closantel |
| Targets: | |
| MoA: | chitinase inhibitor; NFkB pathway inhibitor |
| SMILES: | Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 91197 | BRD-A19952358 | HUH7 | 4 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121364 | BRD-A19952358 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121384 | BRD-A19952358 | HA1E | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.94 | 0.37 |
| 121404 | BRD-A19952358 | HELA | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.08 | 0.79 |
| 121507 | BRD-A19952358 | YAPC | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129488 | BRD-A19952358 | HT29 | 0.08 uM | 24 h | 0.31 | 1.29 | 0.66 | -0.22 | -0.75 | 0.06 |
| 129518 | BRD-A19952358 | MCF??7.00 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129551 | BRD-A19952358 | PC3 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |