CMap Candidate Details
Structure:
| CMap ID: | C01354 |
| Pert ID: | BRD-K15916496 |
| Compound Name: | clotrimazole |
| Targets: | CYP3A4|KCNN4|NR1I2|NR1I3|TRPM2|TRPM4|TRPM8 |
| MoA: | cytochrome P450 inhibitor; imidazoline receptor ligand |
| SMILES: | Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 25331 | BRD-K15916496 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.27 | 0.97 | 0.36 |
| 51212 | BRD-K15916496 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.37 | -1.23 | 1.28 |
| 51440 | BRD-K15916496 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.2 | -0.67 | 0.02 |
| 52734 | BRD-K15916496 | HEPG2 | 10 uM | 24 h | 0.27 | 1.14 | 0.31 | 0.0 | 0.0 | 0.0 |
| 53179 | BRD-K15916496 | MCF10A | 10 uM | 24 h | -0.17 | -0.69 | 0.0 | -0.31 | -1.05 | 0.68 |
| 100141 | BRD-K15916496 | U2OS | 10 uM | 6 h | -0.19 | -0.79 | 0.0 | 0.24 | 0.87 | 0.16 |
| 120230 | BRD-K15916496 | A375 | 10 uM | 24 h | 0.21 | 0.86 | 0.01 | 0.19 | 0.67 | 0.01 |
| 120264 | BRD-K15916496 | A549 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120303 | BRD-K15916496 | HA1E | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120335 | BRD-K15916496 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120372 | BRD-K15916496 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.31 | 1.69 |
| 120457 | BRD-K15916496 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |