CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01368
Pert ID:	BRD-A84188517
Compound Name:	coenzyme-i
Targets:	AASS\|ACADS\|ADH1A\|ADH1B\|ADH1C\|ADH4\|ADH5\|ADH7\|AKR1B1\|AKR1C1\|AKR1C2\|AKR1C3\|AKR1C4\|ALDH1A1\|ALDH1A2\|ALDH1A3\|ALDH1B1\|ALDH2\|ALDH3A1\|ALDH3A2\|ALDH3B1\|ALDH3B2\|ALDH4A1\|ALDH5A1\|ALDH6A1\|ALDH7A1\|ALDH9A1\|AMT\|BDH1\|BLVRA\|BLVRB\|CDO1\|CYB5R3\|CYP17A1\|CYP4A11\|DHCR7\|DHFR\|DLAT\|DLD\|EHHADH\|GAPDH\|GAPDHS\|GLUD1\|GLUD2\|GPD1\|GSR\|H6PD\|HADH\|HADHA\|HIBADH\|HMGCR\|HMOX1\|HMOX2\|HPGD\|HSD11B1\|HSD11B2\|HSD17B1\|HSD17B10\|HSD17B2\|HSD17B3\|HSD17B4\|HSD17B7\|HSD17B8\|HSD3B1\|HSD3B2\|IDH3A\|IDH3B\|IDH3G\|IMPDH1\|IMPDH2\|LDHA\|LDHAL6A\|LDHAL6B\|LDHB\|LDHC\|MDH1\|MDH2\|ME1\|ME2\|ME3\|MSMO1\|MT-ND1\|MT-ND2\|MT-ND3\|MT-ND4\|MT-ND4L\|MT-ND5\|MT-ND6\|MTHFD1\|MTHFD2\|NDUFA1\|NDUFA10\|NDUFA11\|NDUFA12\|NDUFA13\|NDUFA2\|NDUFA3\|NDUFA4\|NDUFA4L2\|NDUFA5\|NDUFA6\|NDUFA7\|NDUFA8\|NDUFA9\|NDUFAB1\|NDUFB1\|NDUFB10\|NDUFB2\|NDUFB3\|NDUFB4\|NDUFB5\|NDUFB6\|NDUFB7\|NDUFB8\|NDUFB9\|NDUFC1\|NDUFC2\|NDUFS1\|NDUFS2\|NDUFS3\|NDUFS4\|NDUFS5\|NDUFS6\|NDUFS7\|NDUFS8\|NDUFV1\|NDUFV2\|NDUFV3\|NNT\|NQO2\|NSDHL\|OGDH\|PDHA1\|PDHA2\|PDHB\|PHGDH\|PYCR1\|PYCR2\|QDPR\|RDH5\|SORD\|TSTA3\|TYR\|UGDH
MoA:
SMILES:	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)

Summary