CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01372
Pert ID:	BRD-A55416093
Compound Name:	colforsin
Targets:	ADCY2\|ADCY5
MoA:	adenylyl cyclase activator
SMILES:	CC(=O)O[C@H]1[C@@H](O)C2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5405	BRD-A55416093	HA1E	10 uM	6 h	0.0	0.0	0.0	-0.32	-1.08	0.8
5730	BRD-A55416093	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5846	BRD-A55416093	HEPG2	10 uM	6 h	0.24	0.98	0.09	-0.3	-1.01	0.57
6072	BRD-A55416093	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	-0.27	-0.92	0.34
6138	BRD-A55416093	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
6472	BRD-A55416093	VCAP	10 uM	6 h	0.19	0.78	0.0	-0.35	-1.18	1.14
37086	BRD-A55416093	A375	10 uM	6 h	0.0	0.0	0.0	-0.34	-1.16	1.1
37347	BRD-A55416093	A549	10 uM	6 h	0.0	0.0	0.0	-0.37	-1.24	1.35
37519	BRD-A55416093	ASC	10 uM	24 h	0.0	0.0	0.0	-0.39	-1.31	1.7
38024	BRD-A55416093	HT29	10 uM	6 h	0.0	0.0	0.0	-0.35	-1.16	1.11
38368	BRD-A55416093	NPC	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.99	0.5
38872	BRD-A55416093	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
96029	BRD-A55416093	PHH	3.33 uM	24 h	0.0	0.0	0.0	0.26	0.91	0.23

Summary