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CMap Candidate Details

Structure:
CMap ID: C01443
Pert ID: BRD-K40870905
Compound Name: CT-7758
Targets: ITGA4
MoA: integrin antagonist
SMILES: OC(=O)[C@H](Cc1ccc(Nc2nccc3ccncc23)cc1)NC1=C(Br)C(=O)C11CCCCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95538 BRD-K40870905 A549 10 uM 6 h 0.24 1.0 0.11 0.32 1.13 0.82
95623 BRD-K40870905 U2OS 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97321 BRD-K40870905 HAP1 0.66 uM 24 h -0.27 -1.12 0.38 0.26 0.92 0.26
123528 BRD-K40870905 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123549 BRD-K40870905 HA1E 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123603 BRD-K40870905 HEK293 10 uM 24 h 0.29 1.22 0.48 0.0 0.0 0.0
123718 BRD-K40870905 MCF10A 0.04 uM 24 h 0.24 0.98 0.09 0.0 0.0 0.0
123779 BRD-K40870905 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132051 BRD-K40870905 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132067 BRD-K40870905 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132097 BRD-K40870905 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.4 1.42 2.2
132126 BRD-K40870905 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).