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CMap Candidate Details

Structure:
CMap ID: C01477
Pert ID: BRD-A10420615
Compound Name: cyclopiazonic-acid
Targets: ATP2A1
MoA: ATPase inhibitor
SMILES: CC(=O)C1C(=O)[C@@H]2[C@@H]3[C@@H](Cc4cccc5[nH]cc3c45)C(C)(C)N2C1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2956 BRD-A10420615 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.19 1.15
3086 BRD-A10420615 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3425 BRD-A10420615 PC3 10 uM 24 h 0.19 0.77 0.0 -0.25 -0.83 0.17
3663 BRD-A10420615 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39031 BRD-A10420615 A375 10 uM 6 h -0.29 -1.2 0.56 0.0 0.0 0.0
39261 BRD-A10420615 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39547 BRD-A10420615 ASC 10 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
39877 BRD-A10420615 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40163 BRD-A10420615 HT29 10 uM 6 h 0.25 1.03 0.14 -0.34 -1.16 1.1
40419 BRD-A10420615 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.18
40680 BRD-A10420615 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40973 BRD-A10420615 NPC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
41297 BRD-A10420615 SKB 10 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.76
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).