CMap Candidate Details
                      
                      Structure:
                         
                      
                  
                  | CMap ID: | C01562 | 
| Pert ID: | BRD-K20738689 | 
| Compound Name: | dazmegrel | 
| Targets: | TBXAS1 | 
| MoA: | thromboxane synthase inhibitor | 
| SMILES: | Cc1c(Cn2ccnc2)c2ccccc2n1CCC(O)=O | 
| InchiKey: | |
| Compound Aliases: | 
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) | 
|---|---|---|---|---|---|---|---|---|---|---|
| 121515 | BRD-K20738689 | YAPC | 10 uM | 24 h | 0.24 | 1.0 | 0.1 | 0.0 | 0.0 | 0.0 | 
| 129407 | BRD-K20738689 | A375 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.06 | 0.61 | 
| 129438 | BRD-K20738689 | HA1E | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 
| 129466 | BRD-K20738689 | HELA | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 
| 129494 | BRD-K20738689 | HT29 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.08 | 0.79 | 
| 129523 | BRD-K20738689 | MCF??7.00 | 0.01 uM | 24 h | -0.22 | -0.9 | 0.04 | -0.24 | -0.8 | 0.11 | 
| 129556 | BRD-K20738689 | PC3 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 
 
    