Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C01603
Pert ID: BRD-K41170226
Compound Name: deoxycholic-acid
Targets: EFTUD1|FPR1|GPBAR1
MoA: biliverdin reductase A activator; G protein-coupled receptor agonist
SMILES: C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33905 BRD-K41170226 A549 10 uM 6 h -0.24 -1.01 0.17 0.0 0.0 0.0
34103 BRD-K41170226 ASC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
34620 BRD-K41170226 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.88 0.25
34886 BRD-K41170226 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35960 BRD-K41170226 PC3 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
36264 BRD-K41170226 PHH 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.76 0.07
36562 BRD-K41170226 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36822 BRD-K41170226 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98810 BRD-K41170226 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99040 BRD-K41170226 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
123548 BRD-K41170226 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123602 BRD-K41170226 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123633 BRD-K41170226 HELA 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123717 BRD-K41170226 MCF10A 0.37 uM 24 h 0.28 1.18 0.39 0.0 0.0 0.0
123735 BRD-K41170226 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132000 BRD-K41170226 A375 2.22 uM 24 h 0.17 0.69 0.0 -0.32 -1.07 0.75
132066 BRD-K41170226 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132155 BRD-K41170226 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).