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CMap Candidate Details

Structure:
CMap ID: C01608
Pert ID: BRD-K68558722
Compound Name: deracoxib
Targets: PTGS2
MoA: cyclooxygenase inhibitor
SMILES: COc1ccc(cc1F)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5229 BRD-K68558722 A375 10 uM 6 h 0.0 0.0 0.0 0.31 1.11 0.72
5357 BRD-K68558722 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5673 BRD-K68558722 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
6295 BRD-K68558722 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6364 BRD-K68558722 VCAP 10 uM 24 h -0.25 -1.04 0.22 -0.4 -1.34 1.85
37304 BRD-K68558722 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37718 BRD-K68558722 ASC 10 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.26
37934 BRD-K68558722 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38102 BRD-K68558722 HT29 10 uM 6 h -0.28 -1.15 0.43 -0.35 -1.16 1.11
38218 BRD-K68558722 MCF??7.00 10 uM 24 h 0.24 0.99 0.09 -0.25 -0.84 0.17
38540 BRD-K68558722 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38763 BRD-K68558722 PHH 10 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.03
99391 BRD-K68558722 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).