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CMap Candidate Details

Structure:
CMap ID: C01624
Pert ID: BRD-K47635719
Compound Name: dexamethasone-acetate
Targets:
MoA: glucocorticoid receptor agonist
SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(C)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5209 BRD-K47635719 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5457 BRD-K47635719 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.96 0.42
5641 BRD-K47635719 HCC515 10 uM 24 h -0.19 -0.79 0.0 -0.35 -1.18 1.15
5924 BRD-K47635719 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
6029 BRD-K47635719 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6195 BRD-K47635719 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6559 BRD-K47635719 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37391 BRD-K47635719 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37674 BRD-K47635719 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38207 BRD-K47635719 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38498 BRD-K47635719 NPC 10 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
38735 BRD-K47635719 PHH 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.23 1.25
99580 BRD-K47635719 U2OS 4 uM 6 h 0.26 1.08 0.21 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).