CMap Candidate Details
Structure:
| CMap ID: | C01627 |
| Pert ID: | BRD-K58626373 |
| Compound Name: | dexfenfluramine |
| Targets: | HTR2C|SLC6A4 |
| MoA: | serotonin receptor agonist |
| SMILES: | CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123801 | BRD-K58626373 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.27 | 1.43 |
| 123840 | BRD-K58626373 | A549 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123906 | BRD-K58626373 | HEK293 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124007 | BRD-K58626373 | JURKAT | 0.04 uM | 24 h | 0.19 | 0.8 | 0.0 | -0.36 | -1.21 | 1.22 |
| 124060 | BRD-K58626373 | MCF10A | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124128 | BRD-K58626373 | MDAMB231 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124189 | BRD-K58626373 | THP1 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124241 | BRD-K58626373 | YAPC | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132167 | BRD-K58626373 | HA1E | 0.03 uM | 24 h | 0.27 | 1.14 | 0.32 | 0.0 | 0.0 | 0.0 |
| 132199 | BRD-K58626373 | HELA | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132231 | BRD-K58626373 | HT29 | 0.74 uM | 24 h | 0.22 | 0.91 | 0.03 | 0.0 | 0.0 | 0.0 |
| 132255 | BRD-K58626373 | MCF??7.00 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132299 | BRD-K58626373 | PC3 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |