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CMap Candidate Details

Structure:
CMap ID: C01664
Pert ID: BRD-A51078674
Compound Name: diclofensine
Targets: DRD1|MAOA|MAOB
MoA: dopamine reuptake inhibitor
SMILES: COc1ccc2C(CN(C)Cc2c1)c1ccc(Cl)c(Cl)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123811 BRD-A51078674 A375 0.125 uM 24 h 0.23 0.94 0.06 0.22 0.77 0.06
123851 BRD-A51078674 A549 0.125 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
123920 BRD-A51078674 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123952 BRD-A51078674 HELA 10 uM 24 h 0.2 0.82 0.0 -0.25 -0.86 0.21
124022 BRD-A51078674 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.81
124073 BRD-A51078674 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124103 BRD-A51078674 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.72
124203 BRD-A51078674 THP1 0.37 uM 24 h 0.17 0.72 0.0 -0.23 -0.79 0.11
124256 BRD-A51078674 YAPC 10 uM 24 h 0.22 0.91 0.03 0.31 1.1 0.7
132177 BRD-A51078674 HA1E 2.22 uM 24 h 0.24 1.0 0.11 -0.23 -0.76 0.07
132241 BRD-A51078674 HT29 0.03 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.17
132279 BRD-A51078674 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132310 BRD-A51078674 PC3 0.25 uM 24 h -0.23 -0.94 0.08 -0.34 -1.14 1.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).