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CMap Candidate Details

Structure:
CMap ID: C01671
Pert ID: BRD-K84794093
Compound Name: dideoxyadenosine
Targets:
MoA: nucleoside reverse transcriptase inhibitor
SMILES: Nc1ncnc2n(cnc12)[C@H]1CC[C@@H](CO)O1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125987 BRD-K84794093 A549 0.125 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
126011 BRD-K84794093 HA1E 10 uM 24 h 0.21 0.88 0.01 0.0 0.0 0.0
126035 BRD-K84794093 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126140 BRD-K84794093 JURKAT 0.37 uM 24 h 0.24 1.02 0.13 0.32 1.12 0.76
126193 BRD-K84794093 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126311 BRD-K84794093 THP1 0.125 uM 24 h -0.23 -0.97 0.11 0.0 0.0 0.0
134015 BRD-K84794093 A375 0.74 uM 24 h -0.26 -1.09 0.33 0.31 1.09 0.67
134114 BRD-K84794093 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134188 BRD-K84794093 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134210 BRD-K84794093 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134234 BRD-K84794093 MCF??7.00 2.22 uM 24 h -0.25 -1.02 0.19 0.3 1.05 0.58
134268 BRD-K84794093 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134291 BRD-K84794093 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134322 BRD-K84794093 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).