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CMap Candidate Details

Structure:
CMap ID: C01676
Pert ID: BRD-K45330754
Compound Name: diethylstilbestrol
Targets: ESR1|ESR2|ESRRB|ESRRG
MoA: estrogen receptor agonist
SMILES: CC\C(c1ccc(O)cc1)=C(\CC)c1ccc(O)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5777 BRD-K45330754 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6553 BRD-K45330754 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42368 BRD-K45330754 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43556 BRD-K45330754 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43856 BRD-K45330754 PHH 10 uM 24 h 0.22 0.92 0.04 -0.2 -0.67 0.01
44121 BRD-K45330754 SKB 10 uM 24 h 0.25 1.02 0.13 0.0 0.0 0.0
53030 BRD-K45330754 HEPG2 30 uM 48 h -0.25 -1.02 0.19 0.0 0.0 0.0
53114 BRD-K45330754 MCF10A 100 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
125233 BRD-K45330754 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125272 BRD-K45330754 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.36
125296 BRD-K45330754 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125348 BRD-K45330754 HELA 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
125391 BRD-K45330754 JURKAT 1.11 uM 24 h -0.3 -1.24 0.65 -0.38 -1.27 1.43
125432 BRD-K45330754 MCF??7.00 0.37 uM 24 h -0.26 -1.09 0.31 -0.28 -0.95 0.42
125542 BRD-K45330754 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133355 BRD-K45330754 A549 2.22 uM 24 h 0.0 0.0 0.0 -0.35 -1.16 1.11
133443 BRD-K45330754 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133541 BRD-K45330754 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.31
133577 BRD-K45330754 PC3 0.03 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.72
133596 BRD-K45330754 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).