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CMap Candidate Details

Structure:
CMap ID: C01701
Pert ID: BRD-K10974103
Compound Name: diloxanide
Targets:
MoA: protein synthesis inhibitor
SMILES: CN(C(=O)C(Cl)Cl)c1ccc(OC(=O)c2ccco2)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5429 BRD-K10974103 HA1E 10 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.32
5757 BRD-K10974103 HCC515 10 uM 6 h -0.25 -1.06 0.25 0.24 0.84 0.13
5881 BRD-K10974103 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6162 BRD-K10974103 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6522 BRD-K10974103 VCAP 10 uM 6 h 0.28 1.15 0.34 0.28 1.0 0.43
37123 BRD-K10974103 A375 10 uM 6 h -0.26 -1.1 0.35 0.23 0.8 0.08
37266 BRD-K10974103 A549 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
37592 BRD-K10974103 ASC 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.05
38054 BRD-K10974103 HT29 10 uM 6 h -0.3 -1.26 0.71 0.0 0.0 0.0
38427 BRD-K10974103 NPC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
38689 BRD-K10974103 PHH 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.93
52126 BRD-K10974103 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.43 -1.45 15.35
100072 BRD-K10974103 U2OS 6.66 uM 6 h 0.2 0.85 0.01 -0.2 -0.67 0.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).