CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01717
Pert ID:	BRD-K92848252
Compound Name:	diminazene-aceturate
Targets:	AOC1\|PRDX5\|PRSS1
MoA:	angiotensin converting enzyme activator
SMILES:	NC(=N)c1ccc(N\N=N\c2ccc(cc2)C(N)=N)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
128370	BRD-K92848252	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128419	BRD-K92848252	HEK293	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128529	BRD-K92848252	JURKAT	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128622	BRD-K92848252	MDAMB231	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128672	BRD-K92848252	PC3	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128702	BRD-K92848252	THP1	1.11 uM	24 h	0.0	0.0	0.0	0.28	0.98	0.38
128753	BRD-K92848252	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136163	BRD-K92848252	A375	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136209	BRD-K92848252	HA1E	0.03 uM	24 h	0.26	1.07	0.2	0.0	0.0	0.0
136251	BRD-K92848252	HELA	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136284	BRD-K92848252	HT29	0.03 uM	24 h	0.0	0.0	0.0	-0.24	-0.8	0.11
136302	BRD-K92848252	MCF10A	0.01 uM	24 h	0.0	0.0	0.0	-0.37	-1.24	1.3
136330	BRD-K92848252	MCF??7.00	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary