CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01722
Pert ID:	BRD-K26521938
Compound Name:	dinoprostone
Targets:	CATSPER1\|CATSPER2\|CATSPER3\|CATSPER4\|PTGDR\|PTGDR2\|PTGER1\|PTGER2\|PTGER3\|PTGER4\|PTGFR\|TBXA2R
MoA:	prostanoid receptor agonist
SMILES:	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1570	BRD-K26521938	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
2097	BRD-K26521938	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
2301	BRD-K26521938	PC3	10 uM	24 h	-0.19	-0.79	0.0	0.0	0.0	0.0
2789	BRD-K26521938	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.38	-1.28	1.45
42082	BRD-K26521938	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
42336	BRD-K26521938	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
42662	BRD-K26521938	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.28	0.99	0.39
42967	BRD-K26521938	HT29	10 uM	6 h	0.0	0.0	0.0	0.31	1.1	0.7
43176	BRD-K26521938	MCF??7.00	10 uM	24 h	-0.29	-1.22	0.61	0.0	0.0	0.0
43827	BRD-K26521938	PHH	10 uM	24 h	-0.26	-1.09	0.32	0.24	0.84	0.12
44097	BRD-K26521938	SKB	10 uM	24 h	0.0	0.0	0.0	-0.4	-1.35	2.01
90966	BRD-K26521938	HUH7	10 uM	72 h	-0.24	-1.0	0.15	0.0	0.0	0.0
98801	BRD-K26521938	NPC	10 uM	6 h	0.25	1.05	0.17	0.0	0.0	0.0
98876	BRD-K26521938	NEU	10 uM	24 h	0.0	0.0	0.0	-0.24	-0.8	0.11
99782	BRD-K26521938	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary