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CMap Candidate Details

Structure:
CMap ID: C01734
Pert ID: BRD-K65814004
Compound Name: diphenyleneiodonium
Targets: NOS2|NOS3
MoA: nitric oxide synthase inhibitor
SMILES: [I+]1c2ccccc2-c2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1603 BRD-K65814004 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
1942 BRD-K65814004 HCC515 10 uM 24 h -0.21 -0.89 0.03 0.0 0.0 0.0
2164 BRD-K65814004 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2465 BRD-K65814004 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
41822 BRD-K65814004 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41967 BRD-K65814004 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42436 BRD-K65814004 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42751 BRD-K65814004 HEPG2 10 uM 6 h -0.23 -0.95 0.09 0.0 0.0 0.0
43050 BRD-K65814004 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43346 BRD-K65814004 MCF??7.00 10 uM 6 h -0.18 -0.76 0.0 0.0 0.0 0.0
43616 BRD-K65814004 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43917 BRD-K65814004 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44172 BRD-K65814004 SKB 10 uM 24 h 0.27 1.12 0.26 0.23 0.81 0.09
99346 BRD-K65814004 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).