CMap Candidate Details
Structure:
| CMap ID: | C01736 |
| Pert ID: | BRD-K22936972 |
| Compound Name: | diphenylpyraline |
| Targets: | HRH1|SLC6A3 |
| MoA: | dopamine uptake inhibitor |
| SMILES: | CN1CCC(CC1)OC(c1ccccc1)c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 99756 | BRD-K22936972 | U2OS | 10 uM | 6 h | -0.33 | -1.39 | 1.14 | 0.37 | 1.29 | 1.49 |
| 121376 | BRD-K22936972 | A375 | 1.11 uM | 24 h | -0.24 | -1.0 | 0.15 | 0.0 | 0.0 | 0.0 |
| 121423 | BRD-K22936972 | HELA | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121537 | BRD-K22936972 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129452 | BRD-K22936972 | HA1E | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.19 | 1.15 |
| 129504 | BRD-K22936972 | HT29 | 2.22 uM | 24 h | 0.16 | 0.65 | 0.0 | -0.24 | -0.8 | 0.11 |
| 129536 | BRD-K22936972 | MCF??7.00 | 0.08 uM | 24 h | 0.27 | 1.14 | 0.3 | 0.0 | 0.0 | 0.0 |
| 129565 | BRD-K22936972 | PC3 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |