CMap Candidate Details
Structure:
| CMap ID: | C01749 |
| Pert ID: | BRD-K33459542 |
| Compound Name: | ditolylguanidine |
| Targets: | GRIN1|GRIN2A|GRIN2B|SIGMAR1 |
| MoA: | sigma receptor agonist |
| SMILES: | Cc1ccccc1NC(=N)Nc1ccccc1C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 2866 | BRD-K33459542 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.22 | 1.25 |
| 3177 | BRD-K33459542 | HCC515 | 10 uM | 24 h | -0.22 | -0.93 | 0.07 | 0.0 | 0.0 | 0.0 |
| 3486 | BRD-K33459542 | PC3 | 10 uM | 24 h | -0.26 | -1.08 | 0.31 | 0.0 | 0.0 | 0.0 |
| 3770 | BRD-K33459542 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.98 | 0.47 |
| 44370 | BRD-K33459542 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44567 | BRD-K33459542 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.79 | 0.11 |
| 44930 | BRD-K33459542 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 45229 | BRD-K33459542 | HEPG2 | 10 uM | 6 h | -0.27 | -1.13 | 0.41 | 0.0 | 0.0 | 0.0 |
| 45499 | BRD-K33459542 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 45807 | BRD-K33459542 | MCF??7.00 | 10 uM | 6 h | 0.19 | 0.81 | 0.0 | 0.23 | 0.8 | 0.08 |
| 46048 | BRD-K33459542 | NPC | 10 uM | 24 h | -0.27 | -1.14 | 0.43 | 0.0 | 0.0 | 0.0 |
| 46365 | BRD-K33459542 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.17 | 1.13 |
| 99857 | BRD-K33459542 | U2OS | 10 uM | 6 h | -0.31 | -1.29 | 0.77 | 0.0 | 0.0 | 0.0 |