CMap Candidate Details
Structure:
| CMap ID: | C01774 |
| Pert ID: | BRD-K28029915 |
| Compound Name: | dolasetron |
| Targets: | HTR3A |
| MoA: | serotonin receptor antagonist |
| SMILES: | O=C(O[C@H]1C[C@H]2C[C@H]3C[C@@H](C1)N2CC3=O)c1c[nH]c2ccccc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 21989 | BRD-K28029915 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 22269 | BRD-K28029915 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 22460 | BRD-K28029915 | HA1E | 10 uM | 6 h | 0.3 | 1.24 | 0.53 | 0.0 | 0.0 | 0.0 |
| 22730 | BRD-K28029915 | HCC515 | 10 uM | 6 h | 0.28 | 1.16 | 0.35 | 0.0 | 0.0 | 0.0 |
| 23017 | BRD-K28029915 | HEPG2 | 10 uM | 6 h | -0.31 | -1.28 | 0.74 | -0.43 | -1.46 | 15.35 |
| 23322 | BRD-K28029915 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.02 | 0.49 |
| 23836 | BRD-K28029915 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24294 | BRD-K28029915 | VCAP | 10 uM | 6 h | -0.25 | -1.03 | 0.19 | -0.36 | -1.22 | 1.25 |
| 52143 | BRD-K28029915 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.16 | 1.11 |