CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01778
Pert ID:	BRD-K38305202
Compound Name:	domperidone
Targets:	DRD2\|DRD3
MoA:	dopamine receptor antagonist
SMILES:	Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5449	BRD-K38305202	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5619	BRD-K38305202	HCC515	10 uM	24 h	0.25	1.04	0.15	0.29	1.04	0.56
6187	BRD-K38305202	PC3	10 uM	24 h	0.0	0.0	0.0	-0.39	-1.32	1.71
6320	BRD-K38305202	VCAP	10 uM	24 h	0.0	0.0	0.0	0.25	0.89	0.2
37151	BRD-K38305202	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37286	BRD-K38305202	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
37648	BRD-K38305202	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
37900	BRD-K38305202	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
38078	BRD-K38305202	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
38200	BRD-K38305202	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38473	BRD-K38305202	NPC	10 uM	24 h	0.0	0.0	0.0	-0.35	-1.19	1.15
38715	BRD-K38305202	PHH	10 uM	24 h	-0.28	-1.17	0.5	-0.23	-0.78	0.09
38948	BRD-K38305202	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
90948	BRD-K38305202	HUH7	8 uM	72 h	0.0	0.0	0.0	-0.21	-0.71	0.03
99911	BRD-K38305202	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary