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CMap Candidate Details

Structure:
CMap ID: C01781
Pert ID: BRD-K43887077
Compound Name: dopamine
Targets: DBH|DRD1|DRD2|DRD3|DRD4|DRD5|HTR1A|HTR7|SLC6A2|SLC6A3|SLC6A4
MoA: dopamine receptor agonist
SMILES: NCCc1ccc(O)c(O)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
44964 BRD-K43887077 ASC 10 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
45258 BRD-K43887077 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.25 0.89 0.21
46079 BRD-K43887077 NPC 10 uM 24 h -0.25 -1.03 0.19 0.0 0.0 0.0
46396 BRD-K43887077 PHH 10 uM 24 h 0.28 1.16 0.35 0.0 0.0 0.0
46717 BRD-K43887077 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50363 BRD-K43887077 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51148 BRD-K43887077 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
123249 BRD-K43887077 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123325 BRD-K43887077 HELA 0.37 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
123509 BRD-K43887077 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131564 BRD-K43887077 A549 2.22 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
131603 BRD-K43887077 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131643 BRD-K43887077 HEK293 0.01 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.13
131693 BRD-K43887077 HT29 0.08 uM 24 h 0.25 1.06 0.18 0.2 0.71 0.02
131746 BRD-K43887077 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131801 BRD-K43887077 JURKAT 2.22 uM 24 h 0.18 0.75 0.0 0.0 0.0 0.0
131834 BRD-K43887077 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131874 BRD-K43887077 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131906 BRD-K43887077 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131921 BRD-K43887077 PC3 0.25 uM 24 h -0.22 -0.9 0.04 0.0 0.0 0.0
131941 BRD-K43887077 THP1 0.74 uM 24 h -0.27 -1.12 0.39 0.2 0.71 0.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).